Bioextrusion system

The present system relates to a novel process and equipment for Bioextrusion-based Additive Manufacturing, destined to produce mono and multi-material scaffolds containing or not cells and growth factors for Tissue Engineering applications. The fabrication of these scaffolds is made through the extrusion of one or more materials (synthetic and natural biopolymers, bioceramics and polymer/ceramic biocomposites) through a layer-by-layer manufacturing process. The major characteristic of this system is the possibility of extruding multiple materials through a rotational extrusion head that can process high, medium and low viscosity materials at low or high temperatures, and allowing the direct printing of cells. The system also contemplates an automatic sterilization mechanism. The Bioextrusion system is protected by a Portuguese National Patent (Nº 104247).

Laboratory: Biofabrication Lab